Chapter 3: Cell-Cell Communication in Development
Where possible, references have been linked to PubMed, the National Center for Biotechnology Information’s online database of journal article citations. Citations that do not include links to PubMed are either referring to papers that are too old to be included in PubMed, or to books, which are not listed on PubMed.
Acloque, H., M. S. Adams, K. Fishwick, M. Bronner-Fraser and M. A. Nieto. 2009. Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease. J. Clin. Invest. 119: 1438–1449.
PubMed Link
Adams, J. M. and S. Cory. 1998. The Bcl-2 protein family: Arbiters of cell survival. Science 281: 1322–1326.
PubMed Link
Ananthakrishnan, R. and A. Ehrlicher. 2007. The forces behind cell movement. Int. J. Biol. Sci. 3: 303–317.
PubMed Link
Armstrong, P. B. 1989. Cell sorting out: The self-assembly of tissues in vitro. CRC Crit. Rev. Biochem. Mol. Biol. 24: 119–149
PubMed Link.
Aza-Blanc, P., F. A. Ramirez-Weber, M. P. Laget and T. B. Kornberg. 1997. Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor. Cell 89: 1043–1053.
PubMed Link
Babb, S. G. and 9 others. 2005. Zebrafish R-cadherin (Cdh4) controls visual system development and differentiation. Dev. Dyn. 233: 930–945.
PubMed Link
Baehrecke, E. H. 2002. How death shapes life during development. Nature Rev. Mol. Cell Biol. 3: 779–787.
PubMed Link
Bard, J. B. L. 1990. Morphogenesis: The Cellular and Molecular Processes of Developmental Anatomy. Cambridge University Press, Cambridge.
Beachy, P. A. and 7 others. 1997. Multiple roles of cholesterol in hedgehog protein biosynthesis and signaling. Cold Spring Harb. Symp. Quant. Biol. 62: 191–204.
PubMed Link
Behrens, J., J. P. von Kries, M. Kühl, L. Bruhn, D. Wedlich, R. Grosschedl and W. Birchmeier. 1996. Functional interaction of b-catenin with the transcription factor LRF-1. Nature 382: 638–642.
PubMed Link
Berset, T., E. Fröhl, G. Battu, S. Canevacini and A. Hajnal. 2001. Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 during C. elegans vulval development. Science 291: 1055–1058.
PubMed Link
Bissell, M. J., H. G. Hall and G. Parry. 1982. How does the extracellular matrix direct gene expression? J. Theor. Biol. 99: 31–68.
PubMed Link
Bissell, M., I. S. Mian, D. Raditsky and E. Turley. 2003. Tissue-specificity: Structural cues allow diverse phenotypes form a constant genotype. In G. B. Müller and S. A. Newman (eds.), Origin of Organismal Form. MIT Press, Cambridge.
Bitgood, M. J. and A. P. McMahon. 1995. Hedgehog and BMP genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev. Biol. 172:126–158.
PubMed Link
Bitgood, M. J., L. Shen and A. P. McMahon. 1996. Sertoli cell signalling by desert hedgehog regulates the male germline. Curr. Biol. 6: 298–304.
PubMed Link
Bolouri, H. and E. H. Davidson. 2009. The gene regulatory network basis of “community effect,” and analysis of a sea urchin embryo example. Biochim. Biophys. Acta Gene Reg. Mech. 1789(4): 363–374.
PubMed Link
Breitling, R. 2007. Greased hedgehogs: New links between hedgehog signaling and cholesterol metabolism. BioEssays 29: 1085–1094.
PubMed Link
Briscoe, J., D. Guschin and M. Müller. 1994. Signal transduction: Just another signalling pathway. Curr. Biol. 4: 1033–1036.
PubMed Link
Cadigan, K. M. and R. Nusse. 1997. Wnt signaling: A common theme in animal development. Genes Dev. 24: 3286–3306.
PubMed Link
Cales, C., J. F. Hancock, C. J. Marshall and A. Hall. 1988. The cytoplasmic protein GAP is implicated as a target for regulation by the ras gene product. Nature 332: 548–551.
PubMed Link
Carson, D. D., J. P. Tang and J. Julian. 1993. Heparan sulfate proteoglycan (perlecan) expression by mouse embryos during acquisition of attachment competence. Dev. Biol. 155: 97–106.
PubMed Link
Carson, D. D., J.-P. Tang and S. Gay. 1988. Collagens support embryo attachment and outgrowth in vitro: Effects of the Arg-Gly-Asp sequence. Dev. Biol. 127: 368–375.
PubMed Link
Casanova, J. 2007. The emergence of shape: Notions from the study of the Drosophila tracheal system. EMBO Rep. 8: 335–339.
PubMed Link
Cecconi, F., G. Alvarez-Bolado, B. I. Meyer, K. A. Roth and P. Gruss. 1998. Apaf-1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 94: 727–737.
PubMed Link
Cela, C. and M. Llimargas. 2006. Egfr is essential for maintaining epithelial integrity during tracheal remodelling in Drosophila. Development 133: 3115–3125.
PubMed Link
Chen, A. E., D. D. Ginty, C. M. Fan. 2005. Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins. Nature 433: 317–722.
PubMed Link
Chen, W. T., E. Hasegawa, T. Hasegawa, C. Weinstock and K. M. Yamada. 1985. Development of cell-surface linkage complexes in cultured fibroblasts. J. Cell Biol. 100: 1103–1114.
PubMed Link
Chiang, C., L. T. Ying, E. Lee, K. E. Young, J. L. Corden, H. Westphal and P. A. Beachy. 1996. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383: 407–413.
PubMed Link
Chiarugi, P. and E. Giannoni. 2008. Anoikis: A necessary death program for anchorage-dependent cells. Biochem. Pharm. 76: 1352–1364.
PubMed Link
Chitnis, A., D. Henrique, J. Lewis, D. Ish-Horowicz and C. Kintner. 1995. Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila gene Delta. Nature 375: 761–766.
PubMed Link
Co, C., D. T. Wong, S. Gierke, V. Chang and J. Taunton. 2007. Mechanism of actin network attachment to moving membranes: Barbed end capture by N-WASP WH2 domains. Cell 128: 901–913.
PubMed Link
Cooper, M. K., J. A. Porter, K. E. Young and P. A. Beachy. 1998. Teratogen-mediated inhibition of target tissue response to hedgehog signaling. Science 280: 1603–1607.
PubMed Link
Cross, J. C., Z. Werb and S. J. Fisher. 1994. Implantation and the placenta: Key pieces of the development puzzle. Science 266: 1508–1518.
PubMed Link
Cvekl, A. and J. Piatigorsky. 1996. Lens development and crystallin gene expression: Many roles for Pax-6. BioEssays 18: 621–630.
PubMed Link
Daniel, C. W., G. B. Silberstein, K. Van Horn, P. Strickland, S. Robinson. 1989. TGF-b1-induced inhibition of mouse mammary ductal growth: Developmental specificity and characterization. Dev. Biol. 135: 20–30.
PubMed Link
Davis, G. S., H. M. Phillips and M. S. Steinberg. 1997. Germ-layer surface tension and “tissue affinities” in Rana pipiens gastrulae: Quantitative measurement. Dev. Biol. 192: 630–644.
PubMed Link
Davy, A. and P. Soriano. 2005. Ephrin signaling in vivo: Look both ways. Dev. Dyn. 232: 1–10.
PubMed Link
Davy, A. J. Aubin and P. Soriano. 2004. Ephrin-B1 forward and reverse signaling is required for mouse development. Genes Dev. 18: 572–583.
PubMed Link
Deng, C., A. Wynshaw-Boris, F. Zhou, A. Kuo and P. Leder. 1996. Fibroblast growth factor receptor-3 is a negative regulator of bone growth. Cell 84: 911–921.
PubMed Link
Diderot, D. 1782. D’Alembert’s Dream. Reprinted in J. Barzun and R. H. Bowen (eds.), Rameau’s Nephew and Other Works (1956). Doubleday, Garden City, NY, p. 114.
Dorsky, R. I., W. S. Chang, D. H. Rapaport and W. A. Harris. 1997. Regulation of neuronal diversity in the Xenopus retina by Delta signalling. Nature 385: 67–74.
PubMed Link
Duguay, D., R. Foty, and M. S. Steinberg. 2003. Cadherin-mediated cell adhesion and tissue segregation: Qualitative and quantitative determinants. Dev. Biol. 253: 309–323.
PubMed Link
Dutt, A., J.-P. Tang and D. D. Carson. 1987. Lactosaminoglycans are involved in uterine epithelial cell adhesion in vitro. Dev. Biol. 119: 27–37.
PubMed Link
Engler, A., S. Sen, H. Sweeney and D. Discher. Matrix elasticity directs stem cell lineage specification. Cell 126: 677–689.
PubMed Link
Farach, M. C., J. P. Tang, G. L. Decker and D. D. Carson. 1987. Heparin/heparan sulfate is involved in attachment and spreading of mouse embryos in vitro. Dev. Biol. 123: 401–410.
PubMed Link
Félix, M.-A. 2007. Cryptic quantitative evolution of the vulva intercellular signaling network in Caenorhabditis. Curr. Biol. 17: 103–114.
PubMed Link
Foty, R. A. and M. S. Steinberg. 2004. Cadherin-mediated cell-cell adhesion and tissue segregation in relation to malignancy. Int. J. Dev. Biol. 48: 397–409.
PubMed Link
Foty, R. A. and M. S. Steinberg. 2005. The differential adhesion hypothesis: A direct evaluation. Dev. Biol. 278: 255–263.
PubMed Link
Foty, R. A., C. M. Pfleger, G. Forgacs and M. S. Steinberg. 1996. Surface tensions of embryonic cells predict their mutual envelopment behavior. Development 122: 1611–1620.
PubMed Link
Franch-Marro, X. and J. Casanova. 2000. The alternative migratory pathways of the Drosophila tracheal cells are associated with distinct subsets of mesodermal cells. Dev. Biol. 227: 80–90.
PubMed Link
Frisch, S. M. and E. Ruoslahti. 1997. Integrins and anoikis. Curr. Opin. Cell Biol. 9: 701–706.
PubMed Link
Fujiwara, M., T. Uchida, N. Osumi-Yamashita and K. Eto. 1994. Uchida rat (rSey): A new mutant rat with craniofacial abnormalities resembling those of the mouse Sey mutant. Differentiation 57: 31–38.
PubMed Link
Furuta, Y. and B. L. M. Hogan. 1998. BMP4 is essential for lens induction in the mouse embryo. Genes Dev. 12: 3764–3775.
PubMed Link
García-García, M. J. and K. V. Anderson. 2003. Essential role of glycosaminoglycans in Fgf signaling during mouse gastrulation. Cell 114: 727–737.
PubMed Link
Ghabrial, A. S. and M. A. Krasnow. 2006. Social interactions among epithelial cells during tracheal branching morphogenesis. Nature 441: 746–749.
PubMed Link
Giannone, G. and 10 others. 2007. Lamellipodial actin mechanically links myosin activity with adhesion-site formation. Cell 128: 561–575.
PubMed Link
Gilbert-Barness, E. and J. M. Opitz. 1996. Abnormal bone development: Histopathology and skeletal dysplasias. In M. E. Martini-Neri, G. Neri and J. M. Opitz (eds.), Gene Regulation and Fetal Development. March of Dimes Birth Defects Foundation Original Article Series 30: (1). Wiley-Liss, New York, pp. 103–156.
Giudice, G. and R. Just. 1962. Restitution of whole larvae from disaggregated cells of sea urchin embryos. Dev. Biol. 5: 402–411.
PubMed Link
Goustin, A. S. and 9 others. 1985. Coexpression of the sis and myc proto-oncogenes in developing human placenta suggests autocrine control of trophoblast growth. Cell 41: 301–312.
PubMed Link
Grainger, R. M. 1992. Embryonic lens induction: Shedding light on vertebrate tissue determination. Trends Genet. 8: 349–356.
PubMed Link
Greenwald, I. and G. M. Rubin. 1992. Making a difference: The role of cell-cell interactions in establishing separate identities for equivalent cells. Cell 68: 271–281.
PubMed Link
Greenwald, I., P. W. Sternberg and H. R. Horvitz. 1983. The lin-12 locus specifies cell fates in Caenorhabditis elegans. Cell 34: 435–444.
PubMed Link
Grobstein, C. 1955. Tissue disaggregation in relation to determination and stability of cell type. Ann. NY Acad Sci. 60: 1095–1107.
PubMed Link
Grobstein, C. 1956. Trans-filter induction of tubules in mouse metanephrogenic mesenchyme. Exp. Cell Res. 10: 424–440.
PubMed Link
Groner, B. and F. Gouilleux. 1995. Prolactin-mediated gene activation in mammary epithelial cells. Curr. Opin. Genet. Dev. 5: 587–594.
PubMed Link
Guerrero, I. and C. Chiang. 2007. A conserved mechanism of hedgehog gradient formation by lipid modification. Trends Cell Biol. 17: 1–5.
PubMed Link
Gurdon, J. B. 1988. A community effect in animal development. Nature 336: 772–774.
PubMed Link
Gurdon, J. B., A. Mitchell and D. Mahony. 1995. Direct and continuous assessment by cells of their position in a morphogen gradient. Nature 376: 520–521.
PubMed Link
Gurdon, J. B., P. Harger, A. Mitchell and P. Lemaire. 1994. Activin signalling and response to a morphogen gradient. Nature 371: 487–492.
PubMed Link
Hadley, M. A., S. W. Byers, C. A. Su·rez-Quian, H. Kleinman and M. Dym. 1985. Extracellular matrix regulates Sertoli cell differentiation, testicular cord formation, and germ cell development in vitro. J. Cell Biol. 101: 1511–1512.
PubMed Link
Hahn, H. and 20 others. 1996. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85: 841–851.
PubMed Link
Hakamori, S., M. Fukuda, K. Sekiguchi and W. G. Carter. 1984. Fibronectin, laminin, and other extracellular glycoproteins. In K. A. Picz and A. H. Reddi (eds.), Extracellular Matrix Biochem-istry. Elsevier, New York, pp. 229–276.
Hamburgh, M. 1970. Theories of Differentiation. Elsevier, New York.
Hardman, P., E. Landels, A. S. Woolf and B. S. Spooner. 1994. TGF-b1 inhibits growth and branching morphogenesis in embryonic mouse submandibular and sublingual glands in vitro. Dev. Growth Diff. 36: 567–577.
Harris, M. P., J. F. Fallon and R. O. Prum. 2002. Shh-Bmp2 signaling module and the evolutionary origin and diversification of feathers. J. Exp. Zool. 294: 160–176.
PubMed Link
Harrison, R. G. 1933. Some difficulties of the determination problem. Am. Nat. 67: 306–321.
Hatta, K. and M. Takeichi. 1986. Expression of N-cadherin adhesion molecules associated with early morphogenetic events in chick development. Nature 320: 447–449.
PubMed Link
Hay, E. D. 1980. Development of the vertebrate cornea. Int. Rev. Cytol. 63: 263–322.
PubMed Link
He, T.-C. and 8 others. 1998. Identification of c-MYC as a target of the APC pathway. Science 281: 1509–1512.
PubMed Link
Heasman, J., D. Ginsberg, K. Goldstone, T. Pratt, C. Yoshidanaro and C. Wylie. 1994. A functional test for maternally inherited cadherin in Xenopus shows its importance in cell adhesion at the blastula stage. Development 120: 49–57.
PubMed Link
Heasman, J., R. D. Hines, A. P. Swan, V. Thomas and C. C. Wylie. 1981. Primordial germ cells of Xenopus embryos: The role of fibronectin in their adhesion during migration. Cell 27: 437–447.
PubMed Link
Heldin, C.-H., K. Miyazono and P. ten Dijke. 1997. TGF-b signaling from cell membrane to nucleus through SMAD proteins. Nature 390: 465–471.
PubMed Link
Hemesath, T. J., E. R. Price, C. Takemoto, T. Badalian and D. E. Fisher. 1998. MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes. Nature 391: 298–301.
PubMed Link
Hengartner, M. O., R. E. Ellis and H. R. Horvitz. 1992. Caenorhabditis elegans gene ced-9 protects from programmed cell death. Nature 356: 494–499.
PubMed Link
Hill, R. J. and P. W. Sternberg. 1992. The gene lin-3 encodes an inductive signal for vulval development in C. elegans. Nature 358: 470–476.
PubMed Link
Hirsch, M. S., L. E. Lunsford, V. Trinkaus-Randall and K. K. H. Svoboda. 1997. Chondrocyte survival and differentiation in situ are integrin medicated. Dev. Dynam. 210: 249–263.
PubMed Link
Hogan, B. L. M. 1996. Bone morphogenesis proteins: Multifunctional regulators of vertebrate development. Genes Dev. 10: 1580–1594.
PubMed Link
Holtzer, H. 1968. Induction of chondrogenesis: A concept in terms of mechanisms. In R. Gleischmajer and R. E. Billingham (eds.), Epithelial-Mesenchymal Interactions. Williams & Wilkins, Baltimore, pp. 152–164.
Hong, E. and R. Brewster. 2006. N-cadherin is required for the polarized cell behaviors that drive neurulation in the zebrafish. Development 133: 3895–3905.
PubMed Link
Horwitz, A., K. Duggan, R. Greggs, C. Decker and C. Buck. 1986. The cell substrate attachment (CSAT) antigen has properties of a receptor for laminin and fibronectin. J. Cell Biol. 101: 2134–2144.
PubMed Link
Howe, A., A. E. Aplin, S. K. Alahari and R. L. Juliano. 1998. Integrin signaling and cell growth control. Curr. Opin. Cell Biol. 10: 220–231.
PubMed Link
Hsu, Y.-R. and 10 others. 1997. The majority of stem cell factor exists as monomer under physiological conditions. J. Biol. Chem. 272: 6406–6416.
PubMed Link
Hwang, H-Y, S. K. Olson, J. D. Esko and H. R. Horvitz. 2003. Caenorhabditis elegans early embryogenesis and vulval morphogenesis require chondroitin biosynthesis. Nature 423: 439–443.
PubMed Link
Ihle, J. N. 1996. STATs: Signal transducers and activators of transcription. Cell 84: 331–334.
PubMed Link
Ihle, J. N. 2001. The Stat family in cytokine signaling. Curr. Opin. Cell Biol. 13: 211–217.
PubMed Link
Jacobson, A. G. 1963. The determination and positioning of the nose, lens and ear. I. Interactions within the ectoderm, and between the ectoderm and underlying tissues. J. Exp. Zool. 154: 273–283.
PubMed Link
Jacobson, A. G. 1966. Inductive processes in embryonic development. Science 152: 25–34.
PubMed Link
Jacobson, M. D., M. Weil and M. C. Raff. 1997. Programmed cell death in animal development. Cell 88: 347–354.
PubMed Link
Jan, Y. and 8 others. 2004. A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors. Cell 116: 751–762.
PubMed Link
Johnson, R. L. and 10 others. 1996. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272: 1668–1671.
PubMed Link
Johnson, R. L. and M. P. Scott. 1998. New players and puzzles in the hedgehog signaling pathway. Curr. Opin. Genet. Dev. 8: 450–456.
PubMed Link
Jones, C. M., N. Armes and J. C. Smith. 1996. Signalling by TGF-b family members: Short-range effects of Xnr-2 and BMP-4 contrast with the long-range effects of activin. Curr. Biol. 6: 1468–1475.
PubMed Link
Just, E. E. 1939. The Biology of the Cell Surface. Blakiston, Philadelphia.
Kadokawa, Y., I. Fuketa, A. Nose, M. Takeichi and N. Nakatsuji. 1989. Expression of E- and P-cadherin in mouse embryos and uteri during the periimplantation period. Dev. Growth Diff. 31: 23–30.
Kalluri, R. and R. A. Weinberg. 2009. The basics of epithelial-mesenchymal transition. J. Clin. Invest. 119: 1420–1428.
PubMed Link
Katz, W. S. and P. W. Sternberg. 1996. Intercellular signalling in Caenorhabditis elegans vulval pattern formation. Semin. Cell Dev. Biol. 7: 175–183.
Katz, W. S., R. J. Hill, T. R. Clandenin and P. W. Sternberg. 1995. Different levels of the C. elegans growth factor LIN-3 promote distinct vulval precursor fates. Cell 82: 297–307.
PubMed Link
Keeler, R. F. and W. Binns. 1968. Teratogenic compounds of Veratrum californicum (Durand). V. Comparison of cyclopian effects of steroidal alkaloids from the plant and structurally related compounds from other sources. Teratology 1: 5–10.
PubMed Link
Kelley, R. I. and 7 others. 1996. Holoprosencephaly in RSH/Smith-Lemli-Opitz syndrome: Does abnormal cholesterol metabolism affect the function of Sonic hedgehog? Am. J. Med. Genet. 66: 478–484.
PubMed Link
Kimble, J. 1981. Alterations in cell lineage following laser ablation of cells in the somatic gonad of Caenorhabditis elegans. Dev. Biol. 87: 286–300.
PubMed Link
Kintner, C. 1993. Regulation of embryonic cell adhesion by the cadherin cytoplasm domain. Cell 69: 225–236.
PubMed Link
Kirn-Safran, C. B., R. R. Gomes, A. J. Brown and D. D. Carson. 2004. Heparan sulfate proteoglycans: Coordinators of multiple signaling pathways during chondrogenesis. Birth Def. Res. C. 72: 69–88.
PubMed Link
Knudsen, K., A. F. Horwitz and C. Buck. 1985. A monoclonal antibody identifies a glycoprotein complex involved in cell-substratum adhesion. Exp. Cell Res. 157: 218–226.
PubMed Link
Koga, M. and Y. Ohshima. 1995. Mosaic analysis of the let-23 gene function in vulval induction of Caenorhabditis elegans. Development 121: 2655–2666.
PubMed Link
Kölsch, V., T. Seher, G. J. Fernandez-Ballester, L. Serrano and M. Leptin. 2007. Control of Drosophila gastrulation by apical localization of adherens junctions and RhoGEF2. Science 315: 384–386.
PubMed Link
Kopan, R. 2002. Notch: A membrane-bound transcription factor. J. Cell Sci. 115: 1095–1097.
PubMed Link
Korinek, V. and 7 others. 1997. Constitutive transcriptional activation by a b-catenin-Tcf complex in APC/colon carcinoma. Science 275: 1784–1786.
PubMed Link
Kuida, K. and 7 others. 1996. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384: 368–372.
PubMed Link
Kuida, K. and 8 others. 1998. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell 94: 325–337.
PubMed Link
Kurosaka, S. and A. Kashina. 2008. Cell biology of embryonic migration. Birth Def. Res. C Embryol. Today 84: 102–122.
PubMed Link
Lappi, D. A. 1995. Tumor targeting through fibroblast growth factor receptors. Semin. Cancer Biol. 6: 279–288.
PubMed Link
Lecourtois, M. and F. Schweisguth. 1998. Indirect evidence for Delta-dependent intercellular processing of Notch in Drosophila embryos. Curr. Biol. 8: 771–774.
PubMed Link
Leevers, S. J., H. F. Paterson and C. J. Marshall. 1994. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 369: 411–414.
PubMed Link
Legeai-Mallet, L., C. Benoist-Lasselin, A. Munnich and J. Bonaventure. 2004. Overexpression of FGFR3, Stat1, Stat5 and p21Cip1 correlates with phenotypic severity and defective chondrocyte differentiation in FGFR3-related chondrodysplasias. Bone 34: 26–36.
PubMed Link
Linask, K. L. and J. W. Lash. 1988. A role for fibronectin in the migration of avian precardiac cells. I. Dose-dependent effects of fibronectin antibody. Dev. Biol. 129: 315–323.
PubMed Link
Liu, J.-K., M. C. Di Persio and K. S. Zaret. 1991. Extracellular signals that regulate liver transcription factors during hepatic differentiation in vitro. Mol. Cell Biol. 11: 773–784.
PubMed Link
Logan, C. and R. Nusse. 2004. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20: 781–810.
PubMed Link
Lum, L. and P. A. Beachy. 2004. The hedgehog response network: Sensors, switches, and routers. Science 304: 1755–1759.
PubMed Link
Luna, E. J. and A. L. Hitt. 1992. Cytoskeleton-plasma membrane interactions. Science 258: 955–964.
PubMed Link
Maimonides (Moshe ben Maimon). 1190. A Guide for the Perplexed (M. Friedländer, trans.). Dover, New York (1956).
Malikov, V., E. N. Cytrynbraum, A. Kashina, A. Mogilner and V. Rodionov. 2005. Centering of a radial microtubule array by translocation along microtubules spontaneously nucleated in the cytoplasm. Nature Cell Biol. 7: 1213–1218.
PubMed Link
Martins-Green, M. and M. J. Bissell. 1995. Cell-ECM interactions in development. Semin. Dev. Biol. 6: 149–159.
McBeath, R., D. M. Pirone, C. M. Nelson, K. Bhadriraju and C. S. Chen. 2004. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev. Cell. 483–495.
PubMed Link
McCormick, F. 1989. Ras GTPase activating protein: Signal transmitter and signal terminator. Cell 56: 5–8.
PubMed Link
McEwen, D. G. and M. Peifer. 2001. Wnt signaling: The naked truth? Curr. Biol. 11:R524–R526.
PubMed Link
McMahon, A. P. and A. Bradley. 1990. The Wnt-1 (int-1) proto-oncogene is required for the development of a large region of the mouse brain. Cell 62: 1073–1086.
PubMed Link
McMahon, A. P., P. W.Ingham and C. J. Tabin. 2003. Developmental roles and clinical significance of hedgehog signaling. Curr. Top. Dev. Biol. 53: 1–114.
PubMed Link
Meier, S. 1977. Initiation of corneal differentiation prior to cornea-lens association. Cell Tissue Res. 184: 255–267.
PubMed Link
Michino, K., K. Boras-Granic, P. Mill, C. C. Hui and P. A. Hamel. 2003. Shh expression is required for embryonic hair follicle but not mammary gland development. Dev. Biol. 264: 153–165.
PubMed Link
Montgomery, A. M. P., R. A. Reisfeld and D. A. Cheresh. 1994. Integrin avb3 rescues melanoma cells from apoptosis in a three-dimensional dermal collagen. Proc. Natl. Acad. Sci. USA 91: 8856–8860.
PubMed Link
Morris, A. R., J. Drawbridge and M. S. Steinberg. 2003. Axolotl pronephric duct migration requires an epidermally derived, laminin 1-containing extracellular matrix and the integrin receptor a6b1. Development 130: 5601–5608.
PubMed Link
Moscona, A. A. 1961. Rotation-mediated histogenetic aggregation of dissociated cells: A quantifiable approach to cell interaction in vitro. Exp. Cell Res. 22: 455–475.
PubMed Link
Moscona, A. A. 1974. Surface specification of embryonic cells: Lectin receptors, cell recognition, and specific cell ligands. In A. Monroy (ed.), The Cell Surface in Development. Wiley, New York, pp. 67–99.
Muschler, J., A. Lochter, C. D. Roskelley, P. Yurchenko and M. J. Bissell. 1999. Division of labor among the a6b4 integrins, b1 integrins, and an E3 laminin receptor to signal morphogenesis and ?-casein expression in mammary epithelial cells. Mol. Biol. Cell 10: 2817–2828.
PubMed Link
Nakayama, A., M.-T. Nguyen, C. C. Chen, K. Opdecamp, C. A. Hodgkinson and H. Arnheiter. 1998. Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently. Mech. Dev. 70: 155–166.
PubMed Link
Nandadasa, S., Q. Tao, N. R. Menon, J. Heasman and C. Wylie. 2009. N- and E-cadherins in Xenopus are specifically required in the neural and non-neural ectoderm, respectively, for F-actin assembly and morphogenetic movements. Development 136: 1327–1338.
PubMed Link
Nohno, T. W., Y. Kawakami, H. Ohuchi, A. Fujiwara, H. Yoshioka and S. Noji. 1995. Involvement of the sonic hedgehog gene in chick feather formation. Biochem. Biophys. Res. Comm. 206: 33–39.
PubMed Link
Nose, A. and M. Takeichi. 1986. A novel cadherin adhesion molecule: Its expression patterns associated with implantation and organogenesis of mouse embryos. J. Cell Biol. 103: 2649–2658.
PubMed Link
Notenboom, R. G. E., P. A. J. de Poer, A. F. M. Moorman and W. H. Lamers. 1996. The establishment of the hepatic architecture is a prerequisite for the development of a lobular pattern of gene expression. Development 122: 321–332.
PubMed Link
Oberlender, S. A. and R. S. Tuan. 1994. Expression and functional involvement of N-cadherin in embryonic limb chondrogenesis. Development 120: 177–187.
PubMed Link
Ogino, H. and K. Yasuda. 1998. Induction of lens differentiation by activation of a bZIP transcription factor, l-maf. Science 280: 115–118.
PubMed Link
Ohkawara, B., S.-I. Iemura, P. ten Dijke and N. Ueno. 2002. Action range of BMP is defined by its N-terminal basic amino acid core. Curr. Biol. 12: 205–209.
PubMed Link
Padgett, R. W., J. M. Wozney and W. M. Gelbart. 1993. Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo. Proc. Natl. Acad. Sci. USA 90: 2905–2809.
PubMed Link
Podbielski, A. and B. Kreikemeyer 2004. Cell density-dependent regulation: Basic principles and effects on the virulence of Gram-positive cocci. Int. J. Infect. Dis. 8: 81–95.
PubMed Link
Porter, A. G. and S. Dhakshinamoorty. 2004. Apoptosis initiated by dependence reseptors: A new paradigm for cell death? BioEssays 26: 656–664.
PubMed Link
Price, E. R. and 7 others. 1998. Lineage-specific signaling in melanocytes: c-Kit stimulation recruits p300/CBP to microphthalmia. J. Biol. Chem. 273: 17983–17986.
PubMed Link
Reilly, K. M. and D. A. Melton. 1996. Short-range signaling by candidate morphogens of the TGF-b family and evidence for a relay mechanism of induction. Cell 86: 743–754.
PubMed Link
Remak, R. 1852. Arch. path. Anat. Physiol. klin. Med. (Virchow) 4: 375.
Remak, R. 1855. Untersuchungen ilber die Entwickelung der Wirbelthiere. Reimer Verlag, Berlin.
Riddle, R. D., R. L. Johnson, E. Laufer and C. Tabin. 1993. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75: 1401–1416.
PubMed Link
Ritvos, O., T. Tuuri, M. Erämaa, K. Sainio, K. Hilden, L. Saxén and S. F. Gilbert. 1995. Activin disrupts epithelial branching morphogenesis in developing murine kidney, pancreas, and salivary gland. Mech. Dev. 50: 229–246.
PubMed Link
Roberts, D. S. and S. A. Miller. 1998. Apoptosis in cavitation of middle ear space. Anatomical Rec. 251: 286–289.
PubMed Link
Rodionov, V. and G. G. Borisy. 1997. Self-centering activity of cytoplasm. Nature 386: 170–173.
PubMed Link
Rodriguez, I., K. Araki, K. Khatib, J.-C. Martinou and P. Vassalli. 1997. Mouse vaginal opening is an apoptosis-dependent process which can be prevented by the overexpression of Bcl2. Dev. Biol. 184: 115–121.
PubMed Link
Roessler, E. and 7 others. 1996. Mutations in the human Sonic hedgehog gene cause holoprosencephaly. Nature Genet. 14: 357–360.
PubMed Link
Roskelley, C. D., P. Y. Desprez and M. J. Bissell. 1994. Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proc. Natl. Acad. Sci. USA 91: 12378–12382.
PubMed Link
Rousseau, F. and 7 others. 1994. Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia. Nature 371: 252–254.
PubMed Link
Ruoslahti, E. and M. D. Pierschbacher. 1987. New perspectives in cell adhesion: RGD and integrins. Science 238: 491–497.
PubMed Link
Saha, M. S., C. L. Spann and R. M. Grainger. 1989. Embryonic lens induction: More than meets the optic vesicle. Cell Diff. Dev. 28: 153–172.
PubMed Link
Sano, K. and 7 others. 1993. Protocadherins: A family of cadherin-related molecules in central nervous system. EMBO J. 12: 2249–2256.
PubMed Link
Saunders, J. W., Jr. 1980. Developmental Biology. Macmillan, New York.
Saunders, J. W., Jr. and J. F. Fallon. 1966. Cell death and morphogenesis. In M. Locke (ed.), Major Problems of Developmental Biology. Academic Press, New York, pp. 289–314.
Saunders, J. W., Jr., J. M. Cairns and M. T. Gasseling. 1957. The role of the apical ectodermal ridge of ectoderm in the differentiation of the morphological structure of and inductive specificity of limb parts of the chick. J. Morphol. 101: 57–88.
Saxén, L. and J. Wartiovaara 1966. Cell contact and cell adhesion during tissue organization. Int. J. Cancer 1: 271–290.
PubMed Link
Saxén, L., E. Lehtonen, M. Karkinen-Jääskeläinen, S. Nordling and J. Wartiovaara. 1976. Are morphogenetic tissue interactions mediated by transmissable signal substances or through cell contacts. Nature 259: 662–663.
PubMed Link
Schroeder, E. H., J. A. Kisslinger and R. Kopan. 1998. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393: 382–386.
PubMed Link
Seydoux, G. and I. Greenwald. 1989. Cell autonomy of lin-12 function in a cell fate decision in C. elegans. Cell 57: 1237–1246.
PubMed Link
Shaham, S. and H. R. Horvitz. 1996. An alternatively spliced C. elegans ced-4 RNA encodes a novel cell death inhibitor. Cell 86: 201–208.
PubMed Link
Shi, Y. and J. Massagué. 2003. Mechanisms of TGF-b signaling from cell membrane to the nucleus. Cell 113: 685–700.
PubMed Link
Shiang, R. and 7 others. 1994. Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia. Cell 78: 335–342.
PubMed Link
Shields, J. D., M. E. Fleury, C. Yong, A. A. Tomei, G. J. Randolph and M. A. Swartz. 2007. Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell 11: 526–538.
PubMed Link
Shih, C. and R. A. Weinberg. 1982. Isolation of a transforming sequence from a human bladder carcinoma cell line. Cell 29: 161–169.
PubMed Link
Shulman, J. M., N. Perrimon and J. D. Axelrod. 1998. Frizzled signaling and the developmental control of cell polarity. Trends Genet. 14: 452–458.
PubMed Link
Simske, J. S. and S. K. Kim. 1995. Sequential signaling during Caenorhabditis elegans vulval induction. Nature 375: 142–146.
PubMed Link
Slavkin, H. C. and P. Bringas, Jr. 1976. Epithelial mesenchymal interactions during odontogenesis. IV. Morphological evidence for direct heterotypic cell-cell contacts. Dev. Biol. 50: 428–442.
PubMed Link
Spemann, H. and O. Schotté. 1932. Über xenoplatische Transplantation als Mittel zur Analyse der embryonalen Induction. Naturwissenschaften 20: 463–467.
Spritz, R. A., L. B. Gielbel and S. A. Holmes. 1992. Dominant negative and loss-of-function mutations of the c-kit (mast/Stem cell growth factor receptor) proto-oncogene in human piebaldism. Am. J. Hum. Genet. 50: 261–269.
PubMed Link
Standley, H. J., A. M. Zorn and J. B. Gurdon. 2001. eFGF and its mode of action in the community effect during Xenopus myogenesis. Development 128: 1347–1357.
PubMed Link
Steinberg, M. S. 1964. The problem of adhesive selectivity in cellular interactions. In M. Locke (ed.), Cellular Membranes in Development. Academic Press, New York, pp. 321–434.
Steinberg, M. S. 1970. Does differential adhesion govern self-assembly processes in histogenesis? Equilibrium configurations and the emergence of a hierarchy among populations of embryonic cells. J. Exp. Zool. 173: 395–434.
PubMed Link
Steinberg, M. S. and M. Takeichi. 1994. Experimental specification of cell sorting, tissue spreading and specific spatial patterning by quantitative differences in cadherin expression. Proc. Natl. Acad. Sci. USA 91: 206–209.
PubMed Link
Steinberg, M. S. and S. F. Gilbert. 2004. Townes and Holtfreter (1955): Directed movements and selective adhesion of embryonic amphibian cells. J. Exp. Zool. A: Comp. Exp. Biol. 301: 701–706.
PubMed Link
Stern, H. M., A. M. C. Brown and S. D. Hauschka. 1995. Myogenesis in paraxial mesoderm: Preferential induction by dorsal neural tube and by cells expressing Wnt-1. Development 121: 3675–3686.
PubMed Link
Sternberg, P. W. 1988. Lateral inhibition during vulval induction in Caenorhabditis elegans. Nature 335: 551–554.
PubMed Link
Stokoe, D., S. G. Macdonald, K. Cadwallader, M. Symons and J. F. Hancock. 1994. Activation of raf as a result of recruitment to the plasma membrane. Science 264: 1463–1467.
PubMed Link
Streuli, C. H., N. Bailey and M. J. Bissell. 1991. Control of mammary epithelial differentiation: Basement membrane induces tissue specific gene expression in the absence of cell-cell interactions and morphological polarity. J. Cell Biol. 115: 1383–1396.
PubMed Link
Stricker, A. G., Y. Yamamoto and W. R. Jeffery. 2007. The lens controls cell survival in the retina: Evidence from the blind cavefish, Astyanax. Dev. Biol. 311: 512–523.
PubMed Link
Struhl, G. and A. Adachi. 1998. Nuclear access and action of Notch in vivo. Cell 93: 382–386.
PubMed Link
Su, W.-C. S. and 8 others. 1997. Activation of Stat1 by mutant fibroblast growth factor receptor in thanatophoric dysplasia type II dwarfism. Nature 386: 288–292.
PubMed Link
Takeichi, M. 1987. Cadherins: A molecular family essential for selective cell-cell adhesion and animal morphogenesis. Trends Genet. 3: 213–217.
Takeichi, M. 1991. Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251: 1451–1455.
PubMed Link
Takeichi, M., H. S. Ozaka, K. Tokunaga and T. S. Okada. 1979. Experimental manipulation of cell surface to affect cellular recognition mechanisms. Dev. Biol. 70: 195–205.
PubMed Link
Tamkun, J. W., D. W. DeSimone, D. Fonda, R. S. Patel, C. Buck, A. F. Horwitz and R. O. Hynes. 1986. Structure of integrin, a glycoprotein involved in transmembrane linkage between fibronectin and actin. Cell 46: 271–282.
PubMed Link
Tan, P. B., M. R. Lackner and S. K. Kim. 1998. MAP kinase signaling specificity mediated by the LIN-1/Ets/LIN31 WH transcription factor complex during C. elegans vulval induction. Cell 93: 569–580.
PubMed Link
Thibert, C., M.-A. Teillet, F. Lapointe, L. Mazelin, N. M. Le Douarin and P. Mehlen. 2003. Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog. Science 301: 843–846.
PubMed Link
Thomas, L. 1992. The Fragile Species. Macmillan, New York.
Thut, C. J., R. B. Rountree, M. Hwa and D. M. Kingsley. 2001. A large-scale in situ screen provides molecular evidence for the induction of eye anterior structures by the developing lens. Dev. Biol. 231: 63–76.
PubMed Link
Ting-Berreth, S. A. and C.-M. Chuong. 1996. Local delivery of TGFb2 can substitute for placode epithelium to induce mesenchymal condensation during skin morphogenesis. Dev. Biol. 179: 347–359.
PubMed Link
Townes, P. L. and J. Holtfreter. 1955. Directed movements and selective adhesion of embryonic amphibian cells. J. Exp. Zool. 128: 53–120.
Vaahtokari, A., T. Aberg and I. Thesleff. 1996. Apoptosis in the developing tooth: Association with an embryonic signaling center and suppression by EGF and FGF-4. Development 122: 121–129.
PubMed Link
Vaux, D. L., I. L. Weissman and S. K. Kim. 1992. Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2. Science 258: 1955–1957.
PubMed Link
Vogel-Höpker, A., T. Momose, H. Rohrer, K. Yasua, L. Ishihara and D. H. Rappaport. 2000. Multiple functions of fibroblast growth factor-8 (FGF-8) in chick eye development. Mech. Dev. 94: 25–36.
PubMed Link
Waddington, C. H. 1940. Organisers and Genes. Cambridge University Press, Cambridge.
Wallberg, A. E., K. Pedersen, U. Lendahl and R. G. Roeder. 2002. p300 and PCAF act cooperatively to mediate transcriptional activation from chromatin templates by Notch intracellular domains in vitro. Mol. Cell Biol. 22: 7812–7819.
PubMed Link
Wang, S. and 7 others. 1998. Notch receptor activation inhibits oligodendrocyte differentiation. Neuron 21: 63–76.
PubMed Link
Wary, K. K., A. Mariotti, C. Zurzolo and F. Giancotti. 1998. A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth. Cell 94: 625–634.
PubMed Link
Webster, M. K. and D. J. Donoghue. 1996. Constitutive activation of fibroblast growth factor receptor 3 by the transmembrane domain point mutation found in achondroplasia. EMBO J. 15: 520–527.
PubMed Link
Wilkinson, H. A., K. Fitzgerald and I. Greenwald. 1994. Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision. Cell 79: 1187–1198.
PubMed Link
Willert, K. and 7 others. 2003. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423: 448–452.
PubMed Link
Winter, C. G., B. Wang, A. Ballew, A. Royou, R. Karess, J. D. Axelrod and L. Luo. 2001. Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton. Cell 105: 81–91.
PubMed Link
Witte, O. N. 1990. Steel locus defines new multipotent growth factor. Cell 63: 5–6.
PubMed Link
Woolner, S. 2007. Morphogenesis: Joining the dots to shape an embryo. Curr. Biol. 17: R289–R291.
PubMed Link
Wu, M. and 7 others. 2000. c-Kit triggers dual phosphorylation, which couples activation and degradation of the essential melanocyte factor Mi. Genes Dev. 14: 301–312.
PubMed Link
Yang, E. V., L. Wang and R. A. Tassava. 2005. Effects of exogenous FGF-1 treatment on regeneration of the lens and the neural retina in the newt, Notophthalmus viridescens. J. Exp. Zool. 303A: 837–844.
PubMed Link
Yoo, A. S. and I. Greenwald. 2005. LIN-12/Notch activation leads to microRNA-mediated down-regulation of Vav in C. elegans. Science 310:1330–1333.
PubMed Link
Yoshida, H. and 7 others. 1998. Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 94: 739–750.
PubMed Link
Zhu, J., M. B. Miller, R. E. Vance, B. L. Bassler and J. J. Mekalanos. 2002. Quorum-sensing regulators control virulence gene expression in Vibrio cholerae. Proc. Natl. Acad. Sci. USA 99: 3129–3134.
PubMed Link
Zygar, C. A., T. L. Cook, Jr. and R. M. Grainger. 1998. Gene activation during early stages of lens induction in Xenopus. Development 125: 3509–3519.
PubMed Link