Chapter 11: Paraxial and Intermediate Mesoderm

Where possible, references have been linked to PubMed, the National Center for Biotechnology Information’s online database of journal article citations. Citations that do not include links to PubMed are either referring to papers that are too old to be included in PubMed, or to books, which are not listed on PubMed.

Aitkenhead, M., B. Christ, A. Eichmann, M. Feucht, D. J. Wilson and J. Wilting. 1998. Paracrine and autocrine regulation of vascular endothelial growth factor during tissue differentiation in the quail. Dev. Dyn. 212: 1–13.
PubMed Link

Aoyama, H. and K. Asamoto. 2000. The developmental fate of the rostral/caudal half of a somite for vertebra and rib formation: Experimental confirmation of the resegmentation theory using chick-quail chimeras. Mech. Dev. 99: 71–82.
PubMed Link

Armand, O., A. M. Boutineau, A. Mauger, M. P. Pautou and M. Kieny. 1983. A common somitic origin for embryonic muscle progenitors and satellite cells. Arch. Anat. Microsc. Morphol. Exp. 72: 163–181.

Armstrong, J. F., K. Pritchard-Jones, W. A. Bickmore, N. D. Hastie and J. B. L. Bard. 1992. The expression of the Wilms’ tumor gene, WT-1, in the developing mammalian embryo. Mech. Dev. 40: 85–97.
PubMed Link

Ash, P. J., J. F. Loutit and K. M. S. Townsend. 1980. Osteoclasts derived from haematopoietic stem cells. Nature 283: 669–670.
PubMed Link

Aszódi, A., D. Chan, E. Hunziker, J. F. Bateman and R. Fassler. 1998. Collagen II is essential for the removal of the notochord and the formation of intervertebral discs. J. Cell Biol. 143: 1399–1412.
PubMed Link

Atit, R. and 7 others. 2006. b-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse. Dev. Biol. 296: 164–176.
PubMed Link

Aulehla, A. and O. Pourquié. 2008. Oscillating signaling pathways during embryonic development. Curr. Opin. Cell Biol. 20: 632–737.
PubMed Link

Barak, H., L. Rosenfelder, T. M. Schultheiss and R. Reshef. 2005. Cell fate specification along the anterior-posterior axis of the intermediate mesoderm. Dev. Dyn. 232: 901–914.
PubMed Link

Barasch, J. and 10 others. 1999. Mesenchymal to epithelial conversion in rat metanephros is induced by LIF. Cell 99: 377–386.
PubMed Link

Bard, J. B. L. and A. S. A. Ross. 1991. LIF, the ES cell inhibition factor, reversibly blocks nephrogenesis in cultured mouse kidney rudiments. Development 113: 193–198.
PubMed Link

Bard, J. B. L., A. Gordon, L. Sharp and W. Sellers. 2001. Early nephron formation in the developing mouse kidney. J. Anat. 199: 385–392.
PubMed Link

Bard, J. B. L., J. A. Davies, I. Karavanova, E. Lehtonen, H. Sariola and S. Vainio. 1996. Kidney development: The inductive interactions. Semin. Cell Dev. Biol. 7: 195–202.

Barnes, G. L., P. G. Alexander, C. W. Hsu, B. D. Mariani and R. S. Tuan. 1997. Cloning and characterization of chicken paraxis: A regulator of paraxial mesoderm development and somite formation. Dev. Biol. 189: 95–111.
PubMed Link

Basson, M. A. and 13 others. 2005. Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Dev. Cell 8: 229–239.
PubMed Link

Batourina, E. and 8 others. 2002. Distal ureter morphogenesis depends on epithelial cell remodeling mediated by vitamin A and Ret. Nature Genet. 32: 109–115.
PubMed Link

Ben-Yair, R. and C. Kalcheim. 2005. Lineage analysis of the avian dermomyotome sheet reveals the existence of single cells with both dermal and muscle progenitor fates. Development 132: 689–701.
PubMed Link

Bergstrom, D. A. and S. J. Tapscott. 2001. Molecular distinction between specification and differentiation in the myogenic basic helix-loop-helix transcription factor family. Mol. Cell. Biol. 21: 2404–2412.
PubMed Link

Blair, H. C., A. J. Kahn, E. C. Crouch, J. J. Jeffrey and S. L. Teitelbaum. 1986. Isolated osteoclasts resorb the organic and inorganic components of bone. J. Cell Biol. 102: 1164–1172.
PubMed Link

Boettiger, D., M. Enomoto-Iwamoto, H. Y. Yoon, U. Hofer, A. S. Menko and R. Chiquet-Ehrismann. 1995. Regulation of integrin a5b1 affinity during myogenic differentiation. Dev. Biol. 169: 261–272.
PubMed Link

Borycki, A., A. M. Brown and C. P. Emerson Jr. 2000. Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites. Development 127: 2075–2087.
PubMed Link

Bothe, I. and S. Dietrich. 2006. The molecular setup of the avian head mesoderm and its implication for craniofacial myogenesis. Dev. Dyn. 235: 2845–2860.
PubMed Link

Bouchard, M., A. Souabni, M. Mandler, A. Neubüser and M. Busslinger. 2002. Nephric lineage specification by Pax2 and Pax8. Genes Dev. 16: 2958–2970.
PubMed Link

Brand-Saberi, B., J. Wilting, C. Ebensperger and B. Christ. 1996. The formation of somite compartments in the avian embryo. Int. J. Dev. Biol. 40: 411–420.
PubMed Link

Brend, T. and S. A. Holley. 2009. Balancing segmentation and laterality during vertebrate development. Semin. Cell Dev. Biol. 20: 472–478.
PubMed Link

Brent, A. E. and C. J. Tabin. 2004. FGF acts directly on the somitic tendon progenitors through the Ets transcription factors Pea3 and Erm to regulate scleraxis expression. Development 131: 3885–3896.
PubMed Link

Brent, A. E., R. Schweitzer and C. J. Tabin. 2003. A somitic compartment of tendon precursors. Cell 113: 235–248.
PubMed Link

Brent, A. E., T. Braun and C. J. Tabin. 2005. Genetic analysis of interactions between the somatic muscle, cartilage, and tendon cell lineages during mouse development. Development 132: 515–528.
PubMed Link

Brill, G., N. Kahane, C. Carmeli, D. von Schack, Y.-A. Barde and C. Kalcheim. 1995. Epithelial-mesenchymal conversion of dermatome progenitors requires neural tube-derived signals: Characterization of the role of neurotrophin-3. Development 121: 2583–2594.
PubMed Link

Brodbeck, S. and C. Englert. 2004. Genetic determination of nephrogenesis: The Pax/Eya/Six gene network. Pediat. Nephrol. 19: 249–255.
PubMed Link

Bruder, S. P. and A. I. Caplan. 1989. Cellular and molecular events during embryonic bone development. Connect. Tiss. Res. 20: 65–71.
PubMed Link

Buckingham, M. and S. D. Vincent. 2009. Distinct and dynamic myogenic populations in the vertebrate embryo. Curr. Opin. Genet. Dev. 19: 444–453.
PubMed Link

Buckingham, M., L. Bajard, P. Daubas, M. Esner, M. Lagha, F. Relaix and D. Rocancourt. 2006. Myogenic progenitor cells in the mouse embryo are marked by the expression of Pax3/7 genes that regulate their survivial and mygoenic potential. Anat. Embryol. 211: S51–S56.
PubMed Link

Bulman, M. P. and 9 others. 2000. Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis. Nature Genet. 24: 438–441.
PubMed Link

Burgess, R., P. Cserjesi, K. L. Ligon and E. N. Olson. 1995. Paraxis: A basic helix-loop-helix protein expressed in paraxial mesoderm and developing somites. Dev. Biol. 168: 296–306.
PubMed Link

Burke, A. C. and J. L. Nowicki 2003. A new view of patterning domains in the vertebrate mesoderm. Dev. Cell 4: 159–165.
PubMed Link

Carapuço, M., A. Nóvoa, N. Bobola and M. Mallo. 2005. Hox genes specify vertebrate types in the presomitic mesoderm. Genes Dev. 19: 2116–2121.
PubMed Link

Carroll, T. J. and P. D. Vize. 1999. Synergism between Pax-8 and Lim-1 in embryonic kidney development. Dev. Biol. 214: 46–59.
PubMed Link

Carroll, T. J., J. S. Park, S. Hayashi, A. Majumdar and A. P. McMahon. 2005. Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying the organogenesis of the mammalian urogenital system. Dev. Cell 9: 283–292.
PubMed Link

Cebrian, C., R. Guillaume, P. Charles, A. Bikkal and D. Herzlinger. 2004. Cellular interactions and signals controlling urinary tract segmentation. Signaling in Vertebrate Organogenesis. (G. R. Martin and C. Tabin, eds). Abstract, Keystone Symposium. P. 33.

Chen, C.-M., N. Kraut, M. Groudine and H. Weintraub. 1996. I-mf, a novel myogenic repressor, interacts with members of the MyoD family. Cell 86: 731–741.
PubMed Link

Chi, L., S. Zhang, Y. Lin, R. Prunskaite-Hyyryläinen, R. Vuoteenaho, P. Itaränta and S. Vainio. 2004. Sprouty proteins regulate ureteric bud branching by coordinating reciprocal epithelial Wnt11, mesenchymal Gdnf, and stromal Fgf7 signalling during kidney development. Development 131: 3345–3356.
PubMed Link

Chi, X. and 11 others. 2009. Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis. Dev. Cell 17: 199–209.
PubMed Link

Christ, B. and C. P. Ohrdahl. 1995. Early stages of chick somite development. Anat. Embryol. 191: 381–396.
PubMed Link

Christ, B., R. Huang and M. Scaal. 2007. Amniote somite derivatives. Dev. Dyn. 236: 2382–2396.
PubMed Link

Cochard, L. R. 2002. Netter’s Atlas of Human Embryology. MediMedia USA, Peterboro, NJ.

Cooke, J. and E. C. Zeeman. 1976. A clock and wavefront model for control of the number of repeated structures during animal morphogenesis. J. Theor. Biol. 58: 455–476.
PubMed Link

Cossu, G., R. Kelly, S. Tajbakhsh, S. Di Donna, E. Vivarelli and M. Buckingham. 1996a. Activation of different myogenic pathways: myf-5 is induced by the neural tube and MyoD by the dorsal ectoderm in mouse paraxial mesoderm. Development 122: 429–437.
PubMed Link

Cossu, G., S. Tajbakhsh and M. Buckingham. 1996b. How is myogenesis initiated in the embryo? Trends Genet. 12: 218–223.
PubMed Link

Cserjesi, P. and 7 others. 1995. Scleraxix: A basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. Development 121: 1099–1110.
PubMed Link

Dale, J. K., M. Maroto, M.-L. Dequeant, M. Malaper, M. McGrew and O. Pourquié. 2003. Periodic Notch inhibition by Lunatic Fringe underlies the chick segmentation clock. Nature 421: 275–278.
PubMed Link

Darabi, R., F. N. C. Santos and R. C. R. Perlingeiro. 2008. The therapeutic potential of embryonic and adult stem cells for skeletal muscle regeneration. Stem Cell Rev. 4: 217–225.
PubMed Link

David, J. D., W. M. See and C. A. Higginbotham. 1981. Fusion of chick embryo skeletal myoblasts: Role of calcium influx preceding membrane union. Dev. Biol. 82: 297–307.
PubMed Link

Delfini, M.-C. and 7 others. 2009. The timing of emergence of muscle progenitors is controlled by an FGF/ERK/Snail1 pathway. Dev. Biol. 333: 229–237.
PubMed Link

Denkers, N., P. Garcia-Villalba, C. K. Rodesch, K. R. Nielson and T. J. Mauch. 2004. FISHing for chick genes: Triple-label whole mount fluorescence in situ hybridization detects simultaneous and overlapping gene expression in avian embryos. Dev. Dyn. 229: 651–657.
PubMed Link

Dequéant, M. L. and O. Pourquié. 2008. Segmental patterning of the vertebrate embryonic axis. Nature Rev. Genet. 9: 370–382.
PubMed Link

Dietrich, S., F. R. Schubert, C. Healy, P. T. Sharpe and A. Lumsden. 1998. Specification of hypaxial musculature. Development 125: 2235–2249.
PubMed Link

Doherty, K. R. and 7 others. 2005. Normal myoblast fusion requires myoferlin. Development 132: 5565–5575.
PubMed Link

Duan, R. and P. J. Gallagher. 2009. Dependence of myoblast fusion on a cortical actin wall and nonmuscle myosin IIA. Dev. Biol. 325: 374–385.
PubMed Link

Dubrulle, J., M. J. McGrew and O. Pourquié. 2001. FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation. Cell 106: 219–232.
PubMed Link

Dudley, A. T., K. M. Lyons and E. J. Robertson. 1995. A requirement for bone morphogenesis protein-7 during development of the mammalian kidney and eye. Genes Dev. 9: 2795–2807.
PubMed Link

Dunwoodie, S. L., M. Clements, D. B. Sparrow, X. Sa, R. A. Conlon and R. S. P. Beddington. 2002. Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm. Development 129: 1795–1806.
PubMed Link

Durbin, L. and 8 others. 1998. Eph signaling is required for segmentation and differentiation of the somites. Genes Dev. 12: 3096–3109.
PubMed Link

Ekblom, P. and 8 others. 1994. Role of mesenchymal nidogen for epithelial morphogenesis in vitro. Development 120: 2003–2014.
PubMed Link

Ekblom, P., I. Thesleff, L. Saxén, A. Miettinen and R. Timpl. 1983. Transferrin as a fetal growth factor: Acquisition of responsiveness related to embryonic induction. Proc. Natl. Acad. Sci. USA 80: 2651–2655.
PubMed Link

Emery, A. E. 2002. The muscular dystrophies. Lancet 359: 687–695.

Evans, D. J. and D. M. Noden. 2006. Spatial relations between avian craniofacial neural crest and paraxial mesoderm cells. Dev. Dyn. 235: 1310–1325.
PubMed Link

Fan, C. M. and M. Tessier-Lavigne. 1994. Patterning of mammalian somites by surface ectoderm and notochord: Evidence for sclerotome induction by a hedgehog homolog. Cell 79: 1175–1186.
PubMed Link

Gerber, H. P., T. H. Vu,. A. M. Ryan, J. Kowalski, Z. Werb and N. Ferrara. 1999. VEGF couples hypertrophic cartilage remodeling, ossification, and angiogenesis during endochondral bone formation. Nature Med. 5: 623–628.
PubMed Link

Gerhart, J., J. Elder, C. Neely, J. Schure, T. Kvist, K. Knudsen and M. George-Weinstein. 2006. MyoD-positive epiblast cells regulate skeletal muscle differentiation in the embryo. J. Cell Biol. 175: 283–292.
PubMed Link

Gilbert, S. F. and D. Epel. 2009. Ecological Developmental Biology. Sinauer Associates. Sunderland, MA.

Goldbeter, A. and O. Pourquié. 2008. Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways. J. Theor. Biol. 252: 574–585.
PubMed Link

Gomez, C., E. M. Ozbudak, J. Wunderlich, D. Baumann, J. Lewis and O. Pourquié. 2008. Control of segment number in vertebrate embryos. Nature 454: 335–339.
PubMed Link

Grieshammer, U., L. Ma, A. S. Plump, F. Wang, M. Tessier-Lavigne and G. R. Martin. 2004. SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site. Dev. Cell 6: 709–717.
PubMed Link

Grobstein, C. 1955. Induction interaction in the development of the mouse metanephros. J. Exp. Zool. 130: 319–340.

Grobstein, C. 1956. Trans-filter induction of tubules in mouse metanephrogenic mesenchyme. Exp. Cell Res. 10: 424–440.
PubMed Link

Gros, J., M. Manceau, V. Thomé, and C. Marcelle. 2005. A common somitic origin for embryonic progenitors and satellite cells. Nature 435: 954–958.
PubMed Link

Guehring, T., G. Wilde, M. Sumner, T. Grünhagen, G. B. Karney, U. K. Tirlapur and J. P. Urban. 2009. Notochordal intervertebral disc cells: Sensitivity to nutrient deprivation. Arthritis Rheum. 60: 1026–1034.
PubMed Link

Haigh, J. J., H. P. Gerber, N. Ferrara and E. F. Wagner. 2000. Conditional inactivation of VEGF-A in areas of collagen 2a1 expression results in embryonic lethality in the heterozygous state. Development 127: 1445–1453.
PubMed Link

Halata, Z., M. Grim and B. Christ. 1990. Origin of spinal cord meninges, sheaths of peripheral nerves, and cutaneous receptors including Merkel cells. An experimental and ultrastructural study with avian chimeras. Anat. Embryol. 182: 529–537.
PubMed Link

Hall, B. K. and T. Miyake. 1995. Divide, accumulate, differentiate: Cell condensation in skeletal development revisited. Int. J. Dev. Biol. 39: 881–893.
PubMed Link

Harel, I., E. Nathan, L. Tirosh-Finkel, H. Zigdon, N. Guimarães-Camboa, S. M. Evans and E. Tzahor. 2009. Distinct origins and genetic programs of head muscle satellite cells. Dev. Cell 16: 822–832.
PubMed Link

Hatini, V., S. O. Huh, D. Herzlinger, V. C. Soares and E. Lai. 1996. Essential role of stromal morphogenesis in kidney morphogenesis revealed by targeted disruption of winged helix transcription factor, BF-2. Genes Dev. 10: 1467–1478.
PubMed Link

Hatori, M., K. J. Klatte, C. C. Teixeira and I. M. Shapiro. 1995. End labeling studies of fragmented DNA in avian growth plate: Evidence for apoptosis in terminally differentiated chondrocytes. J. Bone Miner. Res. 10: 1960–1968.
PubMed Link

Hatta, K., S. Takagi, H. Fujisawa and M. Takeichi. 1987. Spatial and temporal expression of N-cadherin cell adhesion molecule correlated with morphogenetic processes of chicken embryo. Dev. Biol. 120: 215–227.
PubMed Link

Holley, S. A. and C. Nüsslein-Volhard. 2000. Somitogenesis in zebrafish. Curr. Top. Dev. Biol. 47: 247–277.
PubMed Link

Horsley, V., K. M. Jansen, S. T. Mills and G. K. Pavlath. 2003. IL-4 acts as a myoblast recruitment factor during mammalian muscle growth. Cell 113: 483–494.
PubMed Link

Horton, W. A. 1990. The biology of bone growth. Growth Genet. Horm. 6(2): 1–3.

Hu, H., M. J. Hilton, X. Tu, K. Yu, D. M. Ornitz and F. Long. 2005. Sequential roles of hedgehog and Wnt signaling in osteoblast development. Development 132: 49–60.
PubMed Link

Itäranta, P., Y. Lin, J. Peräsaari, G. Roël, O. Destrée and S. Vainio. 2002. Wnt-6 is expressed in the ureter bud and induces kidney tubule development in vitro. Genesis 32: 259–268.
PubMed Link

Jiang, Y. J., B. L. Aerne, L. Smithers, C. Haddon, D. Ish-Horowicz and J. Lewis. 2000. Notch signalling and the synchronization of the somite segmentation clock. Nature 408: 475–479.
PubMed Link

Johnson, R. L., E. Laufer, R. D. Riddle and C. Tabin. 1994. Ectopic expression of Sonic hedgehog alters dorsal-ventral patterning of somites. Cell 79: 1165–1173.
PubMed Link

Jouve, C., I. Palmeirim, D. Henrique, J. Beckers, A. Gossler, D. Ish-Horowicz and O. Pourquié. 2000. Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesoderm. Development 127: 1421–1429.
PubMed Link

Jouve, C., T. Imura and O. Pourquié. 2002. Onset of segmentation clock in the chick embryo: Evidence for oscillations in the somite precursors in the primitive streak. Development 129: 1107–1117.
PubMed Link

Kahn, A. J. and D. J. Simmons. 1975. Investigation of cell lineage in bone using a chimaera of chick and quail embryonic tissue. Nature 258: 325–327.
PubMed Link

Kajimura, S., P. Seale, K. Kubota, E. Lunsford, J. V. Frangioni, S. P. Gygi and B. M. Spiegelman. 2009. Initiation of myoblast to brown fat switch by a PRDM-C/EBP-b transcriptional complex. Nature 460: 1154–1158.

Karavanov, A. A., I. Karavanova, A. Perantoni and I. B. Dawid. 1998. Expression pattern of the rat Lim-1 homeobox gene suggests a dual role during kidney development. Int. J. Dev. Biol. 42: 61–66.
PubMed Link

Karsenty, G. and E. F. Wagner. 2002. Reaching a genetic and molecular understanding of skeletal development. Dev. Cell 2: 389–406.
PubMed Link

Kassar-Duchossoy, L., E. Giacone, B. Gayraud-Morel, A. Jory, D. Gomès and S. Tajbakhsh. 2005. Pax3/Pax7 mark a novel population of primitive myogenic cells during development. Genes Dev. 19: 1426–1431.
PubMed Link

Kato, N. and H. Aoyama. 1998. Dermomyotomal origin of the ribs as revealed by extirpation and transplantation experiments in chick and quail embryos. Development 125: 3437–3443.
PubMed Link

Kawakami, Y., A. Raya, R. M. Raya, C. Rodríguez-Esteban and J. C. Belmonte. 2005. Retinoic acid signalling links left-right asymmetric patterning and bilaterally symmetric somitogenesis in the zebrafish embryo. Nature 435: 165–171.
PubMed Link

Kieny, M., A. Mauger and P. Segel. 1972. Early regionalization of somitic mesoderm as studied by the development of the axial skeleton of the chick embryo. Dev. Biol. 28: 142–161.
PubMed Link

Kispert, A., S. Vainio and A. P. McMahon. 1998. Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development 125: 4225–4234.
PubMed Link

Klanke, B., M. Simon, W. Röckl, H. A. Weich, H. Stolte and H. J. Gröne. 1998. Effects of vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) on haemodynamics and permselectivity of the isolated perfused rat kidney. Nephrol. Dial. Transplant. 13: 875–885.
PubMed Link

Knudsen, K. A. 1985. The calcium-dependent myoblast adhesion that precedes cell fusion is mediated by glycoproteins. J. Cell Biol. 101: 891–897.
PubMed Link

Knudsen, K. A., S. A. McElwee and L. Myers. 1990. A role for the neural cell adhesion molecule, NCAM, in myoblast interaction during myogenesis. Dev. Biol. 138: 159–168.
PubMed Link

Kobayashi, A., K.-M. Kwan, T. J. Carroll, A. P. McMahon, C. L. Mendelsohn and R. R. Behringer. 2005. Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development. Development 132: 2809–2823.
PubMed Link

Konigsberg, I. R. 1963. Clonal analysis of myogenesis. Science 140: 1273–1284.
PubMed Link

Koseki, C., D. Herzlinger and Q. Al-Auqati. 1992. Apoptosis in metanephric development. J. Cell Biol. 119: 1327–1333.
PubMed Link

Kreidberg, J. A., H. Sariola, J. M. Loring, M. Maeda, J. Pelletier, D. Housman and R. Jaenisch. 1993. WT-1 is required for early kidney development. Cell 74: 679–691.
PubMed Link

Kuang, S., K. Kuroda, F. Le Grand and M. A. Rudnicki. 2007. Asymmetric self-renewal and commitment of satellite stem cells in muscle. Cell 129: 999–1010.
PubMed Link

Kume, T., K.-U. Deng and B. L. M. Hogan. 2000. Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract. Development 127: 1387–1395.
PubMed Link

Kuure, S., A. Popsueva, M. Jakobson, K. Sainio and H. Sariola. 2007. Glycogen synthase kinase-3 inactivation and stabilization of b-catenin induce nephron differentiation in isolated mouse and rat kidney mesenchymes. J. Am. Soc. Nephrol. 18: 1130–1139.
PubMed Link

Langman, J. 1981. Medical Embryology, 4th Ed. Williams & Wilkins, Baltimore.

Larson, W. J. 1998. Essentials of Human Embryology. Churchill-Livingstone, New York.

Lash, J. W. and K. M. Yamada. 1986. The adhesion recognition signal of fibronectin: A possible trigger mechanism for compaction during somitogenesis. In R. Bellairs, D. H. Ede and J. W. Lash (eds.), Somites in Developing Embryos. Plenum, New York, pp. 201–208.

Lassar, A. B., J. N. Buskin, D. Lockshon, R. L. Davis, S. Apone, S. D. Hauschka and H. Weintraub. 1989. MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer. Cell 58: 823–831.
PubMed Link

Le Douarin, N. and M.-A. Tiellet. 1974. Experimental analysis of the migration and differentiation of neuroblasts of the autonomic nervous system and of neuroectodermal derivatives, using a biological cell marking technique. Dev. Biol. 41: 162–184.
PubMed Link

Lee, S. J. 2004. Regulation of muscle mass by myostatin. Annu. Rev. Cell Dev. Biol. 20: 61–86.
PubMed Link

Lehtonen, E., I. Virtanen and L. Saxén. 1985. Reorganization of the intermediate cytoskeleton in induced mesenchyme cells is independent of tubule morphogenesis. Dev. Biol. 108: 481–490.
PubMed Link

Lin, Y. and 8 others. 2001. Induced repatterning of type XVIII collagen expression in ureter bud from kidney to lung: Association with sonic hedgehog and ectopic surfactant protein C. Development 128: 1573–1585.
PubMed Link

Linask, K. K., C. Ludwig, M. D. Han, X. Liu, G. L. Radice and K. A. Knudsen. 1998. N-cadherin/catenin-mediated morphoregulation of somite formation. Dev. Biol. 202: 85–102.
PubMed Link

Luo, G., C. Hofmann, A. L. J. J. Bronckers, M. Sohocki, A. Bradley and G. Karsenty. 1995. BMP-7 is an inducer of nephrogenesis and is also required for eye development and skeletal patterning. Genes Dev. 9: 2808–2820.
PubMed Link

Maeshima, A., D. A. Vaughn, Y. Choi and S. K. Nigam. 2006. Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct. Dev. Biol. 295: 473–485.
PubMed Link

Majumdar, A., S. Vauinio, A. Kispert, J. McMahon and A. McMahon. 2003. Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development 130: 3175–3185.
PubMed Link

Manceau, M., J. Gros, K. Savage, V. Thomé, A. McPherron, B. Paterson and C. Marcelle. 2008. Myostatin promotes the terminal differentiation of embryonic muscle progenitors. Genes Dev. 22: 668–681.
PubMed Link

Manolagas, S. C. and R. L. Jilka. 1995. Bone marrow, cytokines, and bone remodeling. N. Engl. J. Med. 332: 305–310.
PubMed Link

Marcelle, C., M. R. Stark and M. Bronner-Fraser. 1997. Coordinate actions of BMPs, Wnts, Shh and Noggin mediate patterning of the dorsal somite. Development 124: 3955–3963.
PubMed Link

Maroto, M., R. Reshef, A. E. Münsterberg, S. Koester, M. Goulding and A. B. Lassar. 1997. Ectopic Pax-3 activates MyoD and Myf-5 expression in embryonic mesoderm and neural tissue. Cell 89: 139–148.
PubMed Link

Martins, G. G., P. Rifes, R. Amândio, G. Rodrigues, I. Palmeirim and S. Thorsteinsdóttir. 2009. Dynamic 3D cell rearrangements guided by a fibronectin matrix underlie somitogenesis. PLoS One 4: e7429.
PubMed Link

Mauch, T. J., G. Yang, M. Wright, D. Smith and G. C. Schoenwolf. 2000. Signals from trunk paraxial mesoderm induce pronephros formation in chick intermediate mesoderm. Dev. Biol. 220: 62–75.
PubMed Link

McPherron, A. C., A. M. Lawler and S. J. Lee. 1997. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387: 83–90.
PubMed Link

Medvinsky, A. and E. Dzierzak. 1996. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 86: 897–906.
PubMed Link

Meier, S. 1979. Development of the chick embryo mesoblast. Formation of the embryonic axis and establishment of the metameric pattern. Dev. Biol. 73: 25–45.
PubMed Link

Mendelsohn, C. 2009. Using mouse models to understand normal and abnormal urogenital tract development. Organogenesis 5: 306–314.
PubMed Link

Menko, A. S. and D. Boettiger. 1987. Occupation of the extracellular matrix integrin is a control point for myogenic differentiation. Cell 51: 51–57.
PubMed Link

Mintz, B. and W. W. Baker. 1967. Normal mammalian muscle differentiation and gene control of isocitrate dehydrogenase synthesis. Proc. Natl. Acad. Sci. USA 58: 592–598.
PubMed Link

Mittapalli, V. R., R. Huang, K. Patel, B. Christ and M. Scaal. 2005. Arthrotome: A specific joint forming compartment in the avian somite. Dev. Dyn. 234: 48–53.
PubMed Link

Miyazaki, Y., K. Oshima, A. Fogo, B. L. Hogan and I. Ichikawa. 2000. Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter. J. Clin. Invest. 105: 863–873.
PubMed Link

Moore, M. W. and 9 others. 1996. Renal and neuronal abnormalities in mice lacking GDNF. Nature 382: 76–79.
PubMed Link

Morimoto, M., Y. Takahashi, M. Endo and Y. Saga. 2005. The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. Nature 435: 354–359.
PubMed Link

Morin-Kensicki, E. M., E. Melancon and J. S. Eisen. 2002. Segmental relationship between somites and vertebral column in zebrafish. Development 129: 3851–3860.
PubMed Link

Mortlock, D. P. and J. W. Innis. 1997. Mutation of HOXA13 in hand-foot-genital syndrome. Nature Genet. 15: 179–181.
PubMed Link

Mosher, D. S., P. Quignon, C. D. Bustamante, N. B. Sutter, C. S. Mellersh, H. G. Parker and E. A. Ostrander. 2007. A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genet. 3: e79.
PubMed Link

Mugford, J. W., J. Yu, A. Kobayashi and A. P. McMahon. 2009.High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population. Dev. Biol. 333: 312–323.
PubMed Link

Müller, U., D. Wang, S. Denda, J. Menesis, R. Pedersen and L. Reichardt. 1997. Integrin a8b1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesis. Cell 88: 603–613.

Münsterberg, A. E., J. Kitajewski, D. A. Bumcroft, A. P. McMahon and A. B. Lassar. 1995. Combinatorial signaling by sonic hedgehog and Wnt family members induce myogenic bHLH gene expression in the somite. Genes Dev. 9: 2911–2922.
PubMed Link

Nakamura, T., S. Okuda, D. Miller, E. Ruoslahti and W. Border. 1990. Transforming growth factor-b (TGF-b) regulates production of extracellular matrix (ECM) components by glomerular epithelial cells. Kidney Int. 37: 221.

Nakashima, K., X. Zhou, G. Kunkel, Z. Zhang, J. M. Deng, R. R. Behringer and B. de Crombrugghe. 2002. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108: 17–29.
PubMed Link

Nakaya, Y., S. Kuroda, Y. T. Katagiri, K. Kaibuchi and Y. Takahashi. 2004. Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1. Dev. Cell 7: 425–438.
PubMed Link

Nameroff, M. and E. Munar. 1976. Inhibition of cellular differentiation by phospholipase C. II. Separation of fusion and recognition among myogenic cells. Dev. Biol. 49: 288–293.
PubMed Link

Nimmagadda, S., P. Geetha-Loganathan, M. Scaal, B. Christ and R. Huang. 2007. FGFs, Wnts and BMPs mediate induction of VEGFR-2 (Quek-1) expression during avian somite development. Dev. Biol. 305: 421–429.
PubMed Link

Nowicki, J. L. and A. C. Burke. 2000. Hox genes and morphological identity: Axial versus lateral patterning in the vertebrate mesoderm. Development 127: 4265–4275.
PubMed Link

Nowicki, J. L., R. Takimoto and A. C. Burke. 2003. The lateral somitic frontier: Dorso-ventral aspects of anterior-posterior regionalization in the embryo. Mech. Dev. 120: 227–240.
PubMed Link

Oberlender, S. A. and R. S. Tuan. 1994. Expression and functional involvement of N-cadherin in embryonic limb chondrogenesis. Development 120: 177–187.
PubMed Link

Oka, Y. Y. Sato, Y. Hirai, H. Tsuda and Y. Takahashi. 2006. Epimorphin promotes cartilage condensation/sorting during vertebral skeletogenesis. Dev. Bio. In press.

Olguin, H. C. and B. B. Olwin. 2004. Pax7 upregulation inhibits myogenesis and cell cycle progression in satellite cells: A potential mechanism for self-renewal. Dev Biol. 275: 375–388.
PubMed Link

Olivera-Martinez, I., S. Missier, S. Fraboulet, J. Thélu and D. Dhouailly. 2002. Differential regulation of the chick dorsal thoracic dermal progenitors from medial dermamyotome. Development. 129: 4763–4772.
PubMed Link

Ontell, M., D. Hughes and D. Bourke. 1988. Morphometric analysis of the developing mouse soleus muscle. Am. J. Anat. 181: 279–288.
PubMed Link

Ordahl, C. P. 1993. Myogenic lineages within the developing somite. In M. Bernfield (ed.), Molecular Basis of Morphogenesis. Wiley-Liss, New York, pp. 165–170.

Ordahl, C. P. and N. Le Douarin. 1992. Two myogenic lineages within the developing somite. Development 114: 339–353.
PubMed Link

Palmeirim, I., D. Henrique, D. Ish-Horowicz and O. Pourquié. 1997. Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesis. Cell 91: 639–648.
PubMed Link

Pardanaud, L., D. Luon, M. Prigent, L.-M., Bourcheix, M. Catala and F. Dieterlen-Lievre 1996. Two distinct endothelial lineages in ontogeny, one of them related to hemopoiesis. Development 122: 1363–1371.
PubMed Link

Patterson, L. T., M. Pembaur and S. S. Potter. 2001. Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney. Development 128: 2153–2161.
PubMed Link

Penn, B. H., D. A. Bergstrom, F. J. Dilworth, E. Bengal and S. J.Tapscott. 2004. A MyoD-generated feed-forward circuit temporally patterns gene expression during skeletal muscle differentiation. Genes Dev. 18: 2348–2353.
PubMed Link

Penttinen, R. P., S. Kobayashi and P. Bornstein. 1988. Transforming growth factor-b increases mRNA for matrix proteins in the presence and in the absence of the changes in mRNA stability. Proc. Natl. Acad. Sci. USA 85: 1105–1108.
PubMed Link

Perantoni, A. O., L. F. Dove and I. Karavanova. 1995. Basic fibroblast growth factor can mediate the early inductive events in renal development. Proc. Natl. Acad. Sci USA 92: 4696–4700.
PubMed Link

Pichel, J. G. and 11 others. 1996. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382: 73–76.
PubMed Link

Piette, J., J.-L. Bessereau, M. Huchet and J.-P. Changeux. 1990. Two adjacent MyoD1-binding sites regulate expression of the acetylcholine receptor a-subunit gene. Nature 345: 353–355.
PubMed Link

Pinsky, L. 1974. A community of human malformation syndromes involving the Müllerian ducts, distal extremities, urinary tract, and ears. Teratology 9: 65–80.
PubMed Link

Pouget, C., K. Pottin and T. Jaffredo. 2008. Sclerotomal origin of vascular smooth muscle cells and pericytes in the embryo. Dev. Biol. 315: 437–447.
PubMed Link

Pourquié, O. and 9 others. 1996. Lateral and axial signals involved in somite patterning: A role for BMP4. Cell 84: 461–471.
PubMed Link

Pownall, M. E., M. K. Gustafsson and C. P. Emerson, Jr. 2002. Myogenic regulatory factors and the specification of muscle progenitors in vertebrate embryos. Annu. Rev. Cell Dev. Biol. 18: 747–783.
PubMed Link

Preger-Ben Noon, E., H. Barak, N. Guttmann-Raviv and R. Reshef. 2009. Interplay between activin and Hox genes determines the formation of the kidney morphogenetic field. Development 136: 1995–2004.
PubMed Link

Pritchard-Jones, K. and 11 others. 1990. The candidate Wilms’ tumour gene is involved in genitourinary development. Nature 346: 194–197.
PubMed Link

Qiao, J., R. Uzzo, T. Obara-Ishihara, L. Degenstein, E. Fuchs and D. Herzlinger. 1999. FGF-7 modulates ureteric bud growth and nephron number in the developing kidney. Development. 126: 547–554.
PubMed Link

Rajpurohit, R., K. Mansfield, K. Ohyama, D. Ewert and I. M. Shapiro. 1999. Chondrocyte death is linked to development of a mitochondrial membrane permeability transition in the growth plate. J. Cell. Physiol. 179: 287–296.
PubMed Link

Relaix, F., D. Rocancourt, A. Mansouri and. Buckingham. 2005. A Pax3/Pax7-dependent population of skeletal muscle progenitor cells. Nature 435: 948–953.
PubMed Link

Remak, R. 1850. Untersuchungen über die Entwicklung der Wirbeltiere. Remier, Berlin.

Reshef, R., M. Maroto and A. B. Lassar. 1998. Regulation of dorsal somitic cell fates: BMPs and Noggin control the timing and pattern of myogenic regulator expression. Genes Dev. 12: 290–303.
PubMed Link

Richardson, B. E., S. J. Nowak and M. K. Baylies. 2008. Myoblast fusion in fly and vertebrates: New genes, new processes and new perspectives. Traffic 9: 1050–1059.
PubMed Link

Ritvos, O., T. Tuuri, M. Erämaa, K. Sainio, K. Hildén, L. Saxén and S. F. Gilbert. 1995. Activin disrupts epithelial branching morphogenesis in developing murine kidney, pancreas, and salivary gland. Mech. Dev. 50: 229–245.
PubMed Link

Rothenpieler, U. W. and G. R. Dressler. 1993. Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development. Development. 119: 711–720.
PubMed Link

Saga, Y. 2007. Segmental border is defined by the key transcription factor Mesp2, by means of the suppression of Notch activity. Dev. Dyn. 236: 1450–1455.
PubMed Link

Saga, Y., N. Hata, H. Koseki, and M. M. Taketo. 1997. Mesp2: A novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev. 11: 1827–1839.
PubMed Link

Sainio, K. and 10 others. 1997. Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium. Development. 124: 4077–4087.
PubMed Link

Sainio, K. and A. Raatikainen-Ahokas. 1999. Mesonephric kidney: A stem cell factory? Int. J. Dev. Biol. 43: 435–439.
PubMed Link

Sainio, K., D. Nonclercq, M. Saarma, J. Palgi, L. Saxén and H. Sariola. 1994. Neuronal characteristics of embryonic renal stroma. Int. J. Dev. Biol. 38: 77–84.
PubMed Link

Sánchez, M. P., I. Silos-Santiago, J. Frisén, B. He, S. A. Lira and M. Barbacid. 1996. Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382: 70–73.
PubMed Link

Sariola, H. 2002. Nephron induction revisited: From caps to condensates. Curr. Opin. Nephrol. Hypertens. 11: 17–21.
PubMed Link

Sariola, H., K. Holm-Sainio and S. Henke-Fahle. 1989. The effect of neuronal cells on kidney differentiation. Int. J. Dev. Biol. 33: 149–155.
PubMed Link

Sariola, H., P. Ekblom and L. Saxén. 1982. Restricted developmental options of the metanephric mesenchyme. In M. Burger and R. Weber (eds.), Embryonic Development, Part B: Cellular Aspects. Alan R. Liss, New York, pp. 425–431.

Sato, Y. and 8 others. 2008. Notch mediates the segmental specification of angioblasts in somites and their directed migration toward the dorsal aorta in avian embryos. Dev. Cell 14: 890–901.
PubMed Link

Sato, Y. and Y. Takahashi. 2005. A novel signal induces a segmentation fissure by acting in a ventral-to-dorsal direction in the presomitic mesoderm. Dev. Biol. 282: 183–191.
PubMed Link

Sato, Y., K. Yasuda and Y. Takahashi. 2002. Morphological boundary forms by a novel inductive event mediated by Lunatic-Fringe and Notch during somitic segmentation. Development 129: 3633–3644.

Saxén, L. 1970. Failure to demonstrate tubule induction in heterologous mesenchyme. Dev. Biol. 23: 511–523.
PubMed Link

Saxén, L. 1987. Organogenesis of the Kidney. Cambridge University Press, Cambridge.

Schuchardt, A., V. D’Agati, V. Pachnis and F. Constantini. 1996. Renal agenesis and hypodysplasia in ret-k–mutant mice result from defects in ureteric bud development. Development 122: 1919–1929.
PubMed Link

Schweitzer, R. and 7 others. 2001. Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments. Development 128: 3855–3866.
PubMed Link

Shainberg, A., G. Yagil and D. Yaffe. 1969. Control of myogenesis in vitro by Ca2+ concentration in nutritional medium. Exp. Cell Res. 58: 163–167.
PubMed Link

Shakya, R., T. Watanabe and F. Costatini. 2005. The role of GDNF/Ret signaling in ureter bud cell fate and branching morphogenesis. Dev. Cell 8: 65–74.
PubMed Link

Shapiro, I. M., E. E. Golub, S. Kakuta, J. Hazelgrove, J. Havery, B. Chance and P. Frasca. 1982. Initiation of endochondral calcification is related to changes in the redox state of hypertrophic chondrocytes. Science 217: 950–952.
PubMed Link

Shawlot, W. and R. R. Behringer. 1995. Requirement for Lim1 in head-organizer function. Nature 374: 425–430.
PubMed Link

Shearman, R. M. and A. C. Burke. 2009. The lateral somitic frontier in ontogeny and phylogeny. J. Ex. Zool. B. Mol. Dev. Biol. 312B: 603–612.
PubMed Link

Smith, C. A. and R. S. Tuan. 1996. Functional involvement of Pax-1 in somite development: Somite dysmorphogenesis in chick embryos treated with Pax-1 paired-box antisense oligonucleotide. Teratology 52: 333–345.
PubMed Link

Smith, H. 1953. From Fish to Philosopher. Little, Brown, Boston.

Sosic, D., B. Brand-Saberi, C. Schmidt, B. Christ and E. N. Olson. 1997. Regulation of paraxis expression and somite formation by ectoderm- and neural tube-derived signals. Dev. Biol. 185: 229–243.
PubMed Link

Srinivas, S., M. R. Goldberg, T. Watanabe, V. D’Agati, Q. al-Awqati and F. Costantini. 1999. Expression of green fluorescent protein in the ureteric bud of transgenic mice: A new tool for the analysis of ureteric bud morphogenesis. Dev. Genet. 24: 241–251.
PubMed Link

St.-Jacques, B., M. Hammerschmidt and A. P. McMahon. 1999. Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev. 13: 2072–2086.
PubMed Link

Stark, K., S. Vainio, G. Vassileva and A. P. McMahon. 1994. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372: 679–683.
PubMed Link

Stern, H. M., A. M. C. Brown and S. D. Hauschka. 1995. Myogenesis in paraxial mesoderm: Preferential induction by dorsal neural tube and by cells expressing Wnt-1. Development 121: 3675–3686.
PubMed Link

Suetsugu, R., T. Watanabe and Y. Takahashi. 2005. Pax2 is sufficient to convert a presomitic mesoderm to intermediate mesoderm to form kidney tubules. Int. Sympos. Dev. Biol. (abstract)

Tajbakhsh, S., D. Rocancourt, G. Cossu and M. Buckingham. 1997. Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD. Cell 89: 127–138.
PubMed Link

Takahashi, Y. and Y. Sato. 2008. Somitogenesis as a model to study the formation of morphological boundaries and cell epithelialization. Dev. Growth Differ. 50 (Suppl. 1): S149–S155.
PubMed Link

Takahashi, Y., A.-H. Monsoro-Burg, M. Bontoux and N. M. Le Douarin. 1992. A role for Quox8 in the establishment of the dorsoventral pattern during vertebrate development. Proc. Natl. Acad. Sci. USA 89: 10237–10241.
PubMed Link

Takahashi, Y., K. Koizumi, A. Takagi, S. Kitajima, T. Inoue, H. Koseki and Y. Saga. 2000. Mesp2 initiates somite segmentation through the Notch signalling pathway. Nature Genet. 25: 390–396.
PubMed Link

Takahashi, Y., S. Hiraoka, S. Kitajima, T. Inoue, J. Kanno and Y. Saga. 2005. Differential contributions of Mesp1 and Mesp2 to the epithelialization and rostro-caudal patterning of somites. Development 132: 787–796.
PubMed Link

Tam, P. P. 1981. The control of somitogenesis in mouse embryos. J. Embryol. Exp. Morphol. (Suppl.) 65: 103–128.
PubMed Link

Thayer, M. J., S. J. Tapscott, R. L. Davis, W. E. Wright, A. B. Lassar and H. Weintraub. 1989. Positive autoregulation of the myogenic determination gene MyoD1. Cell 58: 241–248.
PubMed Link

Toivonen, S. 1945. Uber die Entwicklung der Vor- und Uriniere beim Kaninchen. Ann. Acad. Sci. Fenn. Ser. A. 8: 1–27.

Tonegawa, A. and Y. Takahashi. 1998. Somitogenesis controlled by Noggin. Dev. Biol. 202: 172–182.
PubMed Link

Tonegawa, A., N. Funayama, N. Ueno and Y. Takahashi. 1997. Mesodermal subdivision along the mediolateral axis in chicken controlled by different concentrations of BMP-4. Development 124: 1975–1984.
PubMed Link

Tsang, T. E. and 9 others. 2000. Lim1 activity is required for intermediate mesoderm differentiation in the mouse embryo. Dev. Biol. 223: 77–90.
PubMed Link

Tseng, Y. H. and 14 others. 2008. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature 454: 1000–1004.
PubMed Link

Tuan, R. S. 1987. Mechanisms and regulation of calcium transport by the chick embryonic chorioallantoic membrane. J. Exp. Zool. [Suppl.] 1: 1–13.
PubMed Link

Tuan, R. S. and M. H. Lynch. 1983. Effect of experimentally induced calcium deficiency on the developmental expression of collagen types in chick embryonic skeleton. Dev. Biol. 100: 374–386.
PubMed Link

van Adelsberg, J., S. Chamberlain and V. D’Agati. 1997. Polycystin expression is temporally and spatially regulated during renal development. Am. J. Physiol. 272: F602–F609.
PubMed Link

van Heyningen, V. and 11 others. 1990. Role for Wilms tumor gene in genital development? Proc. Natl. Acad. Sci. USA 87: 5383–5386.
PubMed Link

Vega, R. B. and 11 others. 2004. Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell 119: 555–566.
PubMed Link

Ward, C. J. and 8 others. 1996. Polycystin, the polycystic kidney disease protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney. Proc. Nat. Acad. Sci. USA 93: 1524–1528.
PubMed Link

Watanabe, T. Y. Sato, J. Kouyama, H. Okano and Y. Takahashi. 2005. Molecular cascade leading to the morphological segmentation during somitogenesis: Ephrin-Eph signaling downstream of Notch and CMeso1. Dev. Biol. 283: 698.

Weintraub, H., S. J. Tapscott, R. L. Davis, M. J. Thayer, M. A. Adam, A. B. Lassar and D. Miller. 1989. Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD. Proc. Natl. Acad. Sci. USA 86:5434–5438.
PubMed Link

Wellik, D. M., P. J. Hawkes and M. R. Capecchi. 2002. Hox11 paralogous genes are essential for metanephric kidney induction. Genes Dev. 16: 1423–1432.
PubMed Link

Wiegreffe, C., B. Christ, R. Huang and M. Scaal. 2007. Sclerotomal origin of smooth muscle cells in the wall of the avian dorsal aorta. Dev. Dyn. 236: 2578–2585.
PubMed Link

Wilm, B., R. G. James, T. M. Schultheiss and B. L. M. Hogan. 2004. The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate. Dev. Biol. 271: 176–189.
PubMed Link

Winslow, B. B., R. Takimoto-Kimura and A. C. Burke. 2007. Global patterning of the vertebrate mesoderm. Dev. Dyn. 236: 2371–2381.
PubMed Link

Wintour, E. M., A. Butkus, L. Earnest and S. Pompolo. 1996. The erythropoietin gene is expressed strongly in the mammalian mesonephric kidney. Blood 88: 3349–3353.
PubMed Link

Wolpert, L. 1998. Principles of Development. Current Biology Press, London.

Wright, E. and 8 others. 1995. The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos. Nature Genet. 9: 15–20.
PubMed Link

Wu, L. N., B. R. Genge, D. G. Dunkelberger, R. Z. LeGeros, B. Concannon and R. E. Wuthier. 1997. Physiochemical characterization of the nucleational core of matrix vesicles. J. Biol. Chem. 272: 4404–4411.
PubMed Link

Xu, P. X., J. Adams, H. Peters, M. C. Brown, S. Heaney and R. Maas. 1999. Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia. Nature Genet. 23: 113–117.
PubMed Link

Yaffe, D. and M. Feldman. 1965. The formation of hybrid multinucleated muscle fibres from myoblasts of different genetic origin. Dev. Biol. 11: 300–317.
PubMed Link

Yagami-Hiromasa, T., T. Sato, T. Kurisaki, K. Kamijo, Y.-I. Nabeshima and A. Fujisawa-Sehara. 1995. A metalloprotease-disintegrin participating in myoblast fusion. Nature 377: 652–656.
PubMed Link

Yin, M., C. Gentili, E. Koyama, M. Zasloff and M. Pacifici. 2002. Antiangiogenic treatment delays chondrocyte maturation and bone formation during limb skeletogenesis. J. Bone Miner. Res. 17: 56–65.
PubMed Link

Zákány, J., M. Kmita, P. Alarcon, J.-L. de la Pompa and D. Duboule. 2001. Localized and transient transcription of Hox genes suggests a link between patterning and the segmentation clock. Cell 106: 207–217.
PubMed Link



© All the material on this website is protected by copyright. It may not be reproduced in any form without permission from the copyright holder.
Home Link